RNA Interference
Gene Expression Regulation Mechanisms
Five Methods for Producing siRNAs
Terminology
- RNAi RNA Interference
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- dsRNA
- double-stranded RNA
- siRNA small interfering RNA
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- miRNA micro interfering RNA
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- ssRNA single strand RNA
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- the passenger (sense) strand
- guide RNAs
- Is not the source sequence for interference.
- the guide (antisense) strand
- antisense RNAs
- Is the source sequence for interference.
- Ago2 Argonaute 2
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Uncategorized
- Ribosome clearance during RNA interference et al. Article
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- Diversification of small RNA pathways underlies germline RNA interference incompetence in wild Caenorhabditis elegans strains et al. Article
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- Mechanisms of epigenetic regulation by C. elegans nuclear RNA interference pathways et al. Article
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- RNA interference in Caenorhabditis elegans: uptake, mechanism, and regulation et al. Article
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- RNA Interference in Caenorhabditis elegans et al. Article
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- Cellular control of protein levels: A systems biology perspective Munro et al. 2023 Review Article
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- Regulation of gene expression through protein-metabolite interactions Hornisch et al. 2025 Review Article
- "While protein levels often correlate with mRNA levels, quantitative investigations have demonstrated a substantial impact of translation and protein degradation on protein expression control."
- "In addition, protein-level regulation appears to play a crucial role in buffering protein abundances against undesirable mRNA expression variation."
- Manipulating gene expression levels in mammalian cell factories: An outline of synthetic molecular toolboxes to achieve multiplexed control Eisenhut et al. 2023 Review Article
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- Transcriptome analyses describe the consequences of persistent HIF-1 over-activation in Caenorhabditis elegans et al. Article
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https://pubmed.ncbi.nlm.nih.gov/34533692/