Terminology

Transgenerational Epigenetic Inheritance (TEI)

The transmission of epigenetic gene regulatory information across generations.

Involves changes that persist to affect progeny that were not exposed to the original trigger (neither in the uterus nor as germ cells).

When progeny are directly exposed to the environmental effect, the effect is not 'transgenerational' but 'intergenerational'.

Barriers to Transgenerational Inheritance in Animals

Epigenetic Mechanisms of Genomic Imprinting: Common Themes in the Regulation of Imprinted Regions in Mammals, Plants, and Insects Macdonald 2012 Review Article: "Genomic imprinting is a form of epigenetic inheritance whereby the regulation of a gene or chromosomal region is dependent on the sex of the transmitting parent. During gametogenesis, imprinted regions of DNA are differentially marked in accordance to the sex of the parent, resulting in parent-specific expression."; "This review examines some examples of the epigenetic mechanisms responsible for genomic imprinting in mammals, plants, and insects."
Intergenerational and transgenerational epigenetic inheritance in animals Perez et al. 2019 Review Article: ?

From Correlation to Causation: The New Frontier of Transgenerational Epigenetic Inheritance et al. Article: ?
Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans et al. Article: ?
Epigenetic dynamics during germline development: insights from Drosophila and C. elegans Gleason et al. 2024 Author Manuscript: "Seminal work in both Drosophila and C. elegans has elucidated the role of various regulators of epigenetic inheritance including (1) histones (2) histone modifying enzymes, and (3) small RNA (sRNA)-dependent epigenetic regulation in the maintenance of germline identity."; "This review highlights recent discoveries of epigenetic regulation during the step-wise changes of transcription and chromatin structure that takes place during germline stem cell self-renewal, maintenance of germline identity, and intergenerational epigenetic inheritance."

Transgenerational inheritance of metabolic disease et al. Article: ?
Epigenetic Perspectives on Maternal Gut Microbiota's Impact on Embryonic and Fetal Development et al. Article: ?
Maternal-fetal cross-talk via the placenta: influence on offspring development and metabolism et al. Article: ?
Epigenetic mechanisms in maternal-fetal crosstalk: inter- and trans-generational inheritance et al. Article: ?