Overview
PTPN22
| Gene | RS ID | Your Genotype | Notes for Your Genotype | Effect allele | Effect allele frequency |
|---|---|---|---|---|---|
| PTPN22 | rs2476601 | AG | increased risk of autoimmune diseases and endometriosis | A | 0.08 |
| PTPN22 | rs6679677 | AC | increased risk of autoimmune diseases | A | 0.08 |
| PTPN22 | rs1310182 | AG | typical risk | G | 0.48 |
Key Takeaways
- The PTPN22 gene helps in regulating the immune system, particularly by controlling the activation of T cells and B cells. This helps keep the immune response in check.
- Genetic variants in the PTPN22 gene are linked to a wide range of autoimmune conditions, such as vitiligo, alopecia areata, thyroid diseases, and juvenile arthritis.
- Environmental factors and other genetic influences also play important roles.