Key Takeaways
- Autoimmune diseases are caused by your immune system targeting and attacking cells in your body. This can result in a number of different problems: joint pain (rheumatoid arthritis), scaly, thick skin (psoriasis), hypothyroidism (Hashimoto’s), and more.
- CTLA4 keeps the immune response under control and not attacking your own cells.
- Variants in CTLA4 increase the risk of a number of autoimmune diseases.
| Gene | RS ID | Your Genotype | Effect Allele | Effect Allele Frequency | Notes About Effect Allele |
|---|---|---|---|---|---|
| CTLA4 | rs231775 | AG | G | 0.37 | Increased risk of autoimmune diseases |
| CTLA4 | rs3087243 | GG | G | 0.57 | Increased risk of autoimmune diseases |