Timescales, rapid, acclimation, stress, shock, incremental, tolerance, habituate, fluctuation, temporal, acute, sustain

Key Words

Theory

• Adaptive preference towards gradual shifts in your environment for maintaining a homeostatic epigenome?
• Towards a unified theory of gradual environmental shifts for epigenetic homeostasis.
  • Is there a universal adaptation towards slow change in environments for epigenetic normalacy?

Questions

• Comparative studies looking at gradual shifts in your environment on your epigenome?
  • Comparative studies looking at environmental acclimation on your epigenome?

Significance

• Would suddenly going from one environment to the next w/o an acclimation period put you at a higher risk for dysfunction/disease?
• A sudden or hyper-extreme environment is better suited to long-term bio-engineering?

Environments

Environments w/ a Baseline Above Zero

• Oxygen (Hypoxia ⟷ Normoxia ⟷ Hyperoxia)
• Metabolite Levels (Deficiency ⟷ Optimal ⟷ Toxicity)
  • Vitamin Levels (Deficiency ⟷ Optimal ⟷ Toxicity)
  • Mineral Levels (Deficiency ⟷ Optimal ⟷ Toxicity)
• Particulate Matter (Pollution ⟷ Clean Air ⟷ Purified Air)
• Drought
• Salinity
• Cold