Idiopathic Pulmonary Fibrosis

Idiopathic

No known cause.

Pulmonary

Affects the lungs.

Fibrosis

Scarring of the tissue.

Dataset

• 18,838 genes

• 103 IPF samples

  • 36 from surgical biopsies
  • 67 from lungs removed during transplant

• 103 non-IPF controls

  • 41 from normal portion of lung cancer biopsies
  • 62 from deceases organ donors without lung disease

• Quantifying how much mRNA content (fragments of cDNA) was found for each gene in each sample.

  • Higher value indicated more expression.

Differential Expression Analysis

Finding genes with differences in expression between two conditions.