Definitions
- Central Dogma
- DNA -> RNA -> Proteins
- Genes
- DNA that makes proteins.
- Genes never change location.
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- Allele
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- Variant of gene.
- A collection of base pairs.
- Base Pair
- A,T,C,G's that make up a gene.
- May change inside of a gene.
- Changes the allele of the gene.
Mendel's First Law
_Law of Segregation
_Independent Assortment
50% chance for each allele to be chosen.
Mono-Hybrid Crosses
A cross that follows the inheritance of 1 trait.
- Trait
- Characteristics of organisms.
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- Discrete
- Either/or, no in-between.
- Controlled by single genes.
- True Breeding
- Plants that always produce offspring identical to themselves.
- A true-breeding plant is homozygous, has discrete genes.
- Cross-Mating
- Each parent passes on one allele.
- Self-Crossing
- Allele crosses with the same allele.
Generations
- P Generation
- Parental Generation
- F1 First Filial
- Offspring of P.
- F2 Second Filial
- Offspring of F1.
Punnet Squares
Multiplication tables for genetics. Shows combination %s.
- Homozygous
- Both alleles of the homologous gene pairs are the same.
- Heterozygous
- In the homologous gene pairs, there are two different alleles from each parent.
- Genotype Ratio
- The allele ratios from a punnet square.
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YY, Yy, yY, yy is a 1:2:1 genotypic ratio.
- Phenotype Ratio
- The expressed trait ratios from a punnet square.
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Y produces yellow, y produces green.
YY, Yy, yY, yy is a 3:1 yellow to green phenotypic ratio. - Y_
- Underscore is wildcard, doesn't matter what allele.
- Only needs one copy of big Y because it is dominant.
Dominance
How two genes interact with each other to determine the phenotype.
Dominance or recessiveness is not absolute.
One allele may be dominant some of the time and recessive if it shows with another allele.
Dominant just means it shoes up with 1 copy of the allele.
- Dominance
- Describes how alleles interact, not the frequency of which they are passed on.
- Gene is functioning to produce a specific phenotype.
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Think of alleles as two speakers, if either works, the sound will play.
- Dominant Gene
- Denoted by uppercase letters.
- If exists, will express.
- Recessive Gene
- Denoted by lowercase letters.
- Only expresses when the dominant trait is absent.
Types of Dominance
- Complete Dominance
- If it exists, it produces the pigment. Overrides the recessive allele.
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Red producing allele always produces a red phenotype if it exists.
- Incomplete Dominance
- Phenotypes blend. Looks different from each parent.
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Red and white producing alleles combine to make pink.
- Co-Dominance
- Both parent alleles show up.
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Both red and white and simultaneously expressed. Spotted colors.